What is Clozapine? A Basic Definition

clozapine
     n : an antipsychotic drug (trade name
         Clozaril) used as a
         sedative and for treatment-resistant schizophrenia; know
         to have few side effects [syn: Clozaril]

Clozapine (Clozaril) News, Updated Regularly

Second-Generation Antipsychotics Not All Superior to Older Drugs - Medscape News
January 2, 2009, 11:26 am

January 2, 2009 ? A meta-analysis finds that only 4 of 9 second-generation antipsychotics were more efficacious than first-generation antipsychotics for schizophrenia, with small to medium effect sizes. In addition, the classification system of ...

Teva to pay $7 million to Massachusetts - MSN MoneyCentral
January 5, 2009, 8:16 am

Teva Pharmaceutical USA Inc. has agreed to pay $7 million to the Massachusetts Medicaid program to settle an investigation that accused Teva of inflating drug prices. Teva reached the settlement with Massachusetts Attorney Martha Coakley?s office ...

Top 10 news stories of 2008 - Burnett County Sentinel
December 30, 2008, 7:48 am

?Without even looking at the past 52 issues of the Burnett County Sentinel, picking the search and ultimate rescue of Keith Kennedy was the obvious choice for the lead in our Top 10 stories of the year. 1. Clock ticking for lost man The clock was ...

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Off-site Clozapine (Clozaril) Links, User Submitted

The following links have been collected through user bookmark submission in the Clozapine_Clozaril category. Please note, because these resources are off-site we cannot guarantee the accuracy or quality of any information.

Sun Dec 14

• Suspected neuroleptic malignant syndrome in a pati...[Ann Pharmacother. 1996] - PubMed Result
• Clozapine and leukocytosis. [J Clin Psychopharmaco l. 1995] - PubMed Result
• Chronic leukocytosis associated with clozapine: a ...[J Clin Psychiatry. 2007] - PubMed Result

Fri Dec 12

• Second-generat ion versus first-generati on antipsychotic drugs for schizophrenia: a meta-analysis. [2008 Dec 4.]: Four of these drugs were better than first-generati on antipsychotic drugs for overall efficacy, with small to medium effect sizes (amisulpride -0.31 [95% CI -0.44 to -0.19, p<0.0001], clozapine -0.52 [-0.75 to -0.29, p<0.0001], olanzapine -0.28 [-0.38 to -0.18, p<0.0001], and risperidone -0.13 [-0.22 to -0.05, p=0.002]).

Thu Dec 4

• Clozapine - Wikipedia, the free encyclopedia

Wed Nov 26

• LORETA functional imaging in antipsychotic- naive a...[Neuropsyc hobiology. 2008] - PubMed Result: compared to unmedicated patients, general increases in slow delta and theta over the frontal-tempor al-occipital corticies, particularly in the temporolimbic areas, increases in alpha1 and alpha2 in the temporal cortex, and increases in beta1 and beta2 in the temporo-occipi tal and posterior limbic areas. clozapine patients had increases in delta+theta in the anterior cingulate and medial frontal cortex as well as decreases in alpha1, beta2, and beta3 in the occipital cortex and posterior limbic areas and decreases in alpha1 and beta2 in the occipital lobe. asdf... more medication specific info in the abstract, I'm not re-paraphrasin g all of this crap

Thu Sep 25

• A Memoir of Schizophrenia - TIME: A schizophrenic with "a graduate degree from Oxford, a law degree from Yale, and a tenured professorship at the University of Southern California.&qu ot;

Sun Aug 24

• A 12-month follow-up study of treating overweight schizophrenic patients with aripiprazole. [Acta Psychiatr Scand. 2008 Sep;118(3):246 -50.]: In routine practice once aripiprazole treatment was started, more than half of the patients remained on aripiprazole and most of them lost weight. Adding aripiprazole to clozapine gave similar weight loss as monotherapy with aripiprazole.

Tue Apr 15

• The Texas Medication Algorithm Project antipsychotic algorithm for schizophrenia: 2006 update.: The recommended number of trials of other antipsychotics that should precede a clozapine trial is 2, but earlier use of clozapine should be considered in the presence of persistent problems...

Sun Mar 9

• A Randomized, Double-Blind Comparison of Clozapine and High-Dose Olanzapine in Treatment-Resi stant Patients With Schizophrenia.: Olanzapine, at higher than customary doses, demonstrated similar efficacy to clozapine in treatment-resi stant schizophrenia and schizoaffectiv e disorder in this study. However, the small sample size precludes definitively concluding that the 2 treatments

Sun Feb 24

• Therapy of behavioral disorders in Parkinson's disease: Therapy of behavioral disorders in Parkinson' ;s disease

Mon Dec 3

• eClozaril

Wed Nov 28

• BMJ BestTreatments :: Conditions :: Schizophrenia :: Clozapine
• Clozapine - Patient UK

Off-site Clozapine Research Links

If you still need additional information on Clozapine then we suggest the following off-site resources. Please note, because these resources are off-site we cannot guarantee the accuracy or quality of any information.